曾珠

博士，副教授，硕士生导师。研究方向：益生菌的功能特性及其机理研究；家蚕肠道微生物。主讲课程：《蚕桑资源综合利用》、《食品生物技术》、《基础生物化学实验课》。

一、教育及工作经历

教育经历

2008-2012 绵阳师范学院                       本科

2012-2018 中国农业大学                       博士

2016-2017 瑞典卡罗林斯卡医学院       联合培养博士

工作经历

2018-2022 第一版主   讲师

2022-至今 第一版主   副教授

二、代表性科研成果

1.代表性科研项目

(1)国家自然科学基金面上项目, 2025.01至2028.12, 50万元, 主持。

(2)国家自然科学基金青年科学基金项目, 2022.01至2024.12, 30万元, 主持。

(3)中央高校基本科研业务费-能力提升项目, 2022.01至2024.12, 30万元, 主持。

(4)中央高校基本科研业务费-博士启动项目, 2019.01至2020.10, 10万元，主持。

2.代表性科研论文

(1)Zhu Zeng, Tianhao Wang, Yi Yang, Yexuan He, Shuwen Deng, Fangyin Dai, Xiaoling Tong*. Novel silk fibroin/chitosan microgel for enhanced probiotic delivery: Improved stability, viability, and targeted release in gastrointestinal conditions. Carbohydrate Polymers, 2025, 368,124191.

(2)Zhu Zeng, Xiaoling Tong, Yi Yang, Yuli Zhang, Shuwen Deng, Guizheng Zhang, Fangyin Dai*. Pediococcus pentosaceus ZZ61 enhances growth performance and pathogenic resistance of silkworm Bombyx mori by regulating gut microbiota and metabolites. Bioresource Technology, 2024, 402, 130821.

(3)Zhu Zeng, Yi Yang, Xinxin Zhong, Fangyin Dai, Shangwu Chen, Xiaoling Tong*. Ameliorative Effects of Lactobacillus paracasei L14 on Oxidative Stress and Gut Microbiota in Type 2 Diabetes Mellitus Rats. Antioxidants, 2023, 12, 1515.

(4)Zhu Zeng, Xiaoxuan Guo, Jinlan Zhang, Qipeng Yuan, Shangwu Chen*. Lactobacillus paracasei modulates the gut microbiota and improves inflammation in type 2 diabetic rats. Food & Function, 2021,12, 6809.

(5)Zhu Zeng, Fanglei Zuo, Harold Marcotte*. Putative Adhesion Factors in Vaginal Lactobacillus gasseri DSM 14869: Functional Characterization. Applied and Environmental Microbiology, 2019, 85: e00800-19.

(6)Zhu Zeng, Qipeng Yuan, Rui Yu, Jinlan Zhang, Huiqin Ma, Shangwu Chen*. Ameliorative Effects of Probiotic Lactobacillus paracasei NL41 on Insulin Sensitivity, Oxidative Stress, and Beta-Cell Function in a Type 2 Diabetes Mellitus Rat Model. Molecular Nutrition & Food Research, 2019, 63, 1900457.

(7)Zhu Zeng, Junyi Luo, Fanglei Zuo, Ying Zhang, Huiqin Ma, Shangwu Chen*. Screening for potential novel probiotic Lactobacillus strains based on high dipeptidyl peptidase IV and α-glucosidase inhibitory activity. Journal of Functional Foods, 2016, 20: 486-495.

(8)Zhu Zeng, Rui Yu, Fanglei Zuo, Bo Zhang, Huiqin Ma, Shangwu Chen*. Recombinant Lactococcus lactis expressing bioactive exendin-4 to promote insulin secretion and beta-cell proliferation in vitro. Applied Microbiology and Biotechnology, 2017, 101: 7177-7186.

(9)Zhu Zeng, Junyi Luo, Fanglei Zuo, Rui Yu, Ying Zhang, Huiqin Ma, Shangwu Chen*. Bifidobacteria possess inhibitory activity against dipeptidyl peptidase‐IV. Letters in Applied Microbiology, 2016, 62: 250-255.

(10)Zhu Zeng, Rui Yu, Fanglei Zuo, Bo Zhang, Deju Peng, Huiqin Ma, Shangwu Chen*. Heterologous Expression and Delivery of Biologically Active Exendin-4 by Lactobacillus paracasei L14. PLoS ONE, 2016, 11: e0165130.

(11)Zhu Zeng, Fanglei Zuo, Rui Yu, Bo Zhang, Huiqin Ma, Shangwu Chen∗. Characterization of a lactose-responsive promoter of ATP-binding cassette (ABC) transporter gene from Lactobacillus acidophilus 05–172. FEMS Microbiology Letters, 2017, 364, fnx167.

(12)曾珠. 乳酸菌作为药物分子粘膜投递载体的研究进展. 生物工程学报，2021， 37(7): 2272-2282.

(13)曾珠, 陈艳玲, 陈尚武*. 具有α-葡萄糖苷酶抑制活性的益生乳酸菌筛选.农业机械学报, 2020, 51(11): 1-9.

(14)张雨丽^#，曾珠^#, 刘艳伟，陆俣伽, 韦伟，鲁成，崔为正，闭立辉，王平阳，张桂征*. 更换饲料对家蚕幼虫肠道细菌组成的影响及关键物种与产茧性能的相关性. 昆虫学报, 2022, 65: 176-186.

3.指导学生获奖

(1)指导本科生多次获批国家级、市级、校级大学生创新创业训练计划项目。

(2)指导本科生毕业论文多次获“第一版主 优秀毕业论文奖”。

(3)指导本科生多次获全国大学生蚕桑生物技术创新大赛特等奖、一等奖等。

三、联系方式

邮箱：zhuzeng12@swu.edu.cn。